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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBB
All Species:
44.55
Human Site:
S25
Identified Species:
98
UniProt:
P07437
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07437
NP_821133.1
444
49671
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Chimpanzee
Pan troglodytes
Q8WP14
444
49773
S25
A
K
F
W
E
V
I
S
D
E
H
A
I
N
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERD7
450
50400
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Rat
Rattus norvegicus
Q6P9T8
445
49782
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09244
444
49652
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Frog
Xenopus laevis
Q91575
444
49709
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Zebra Danio
Brachydanio rerio
NP_942113
444
49654
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24560
447
50129
S25
A
K
F
W
E
I
I
S
D
E
H
G
I
D
A
Honey Bee
Apis mellifera
XP_392313
447
50157
S25
A
K
F
W
E
I
I
S
D
E
H
G
I
D
P
Nematode Worm
Caenorhab. elegans
P41937
444
49782
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Sea Urchin
Strong. purpuratus
XP_791790
447
50098
S25
A
K
F
W
E
V
I
S
D
E
H
G
I
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
N.A.
N.A.
91.3
97.3
N.A.
N.A.
100
99.7
98.6
N.A.
94.4
94.6
93
96.2
Protein Similarity:
100
95.2
N.A.
N.A.
N.A.
95.1
98.8
N.A.
N.A.
100
99.7
99.5
N.A.
97.7
98.2
97.5
98.4
P-Site Identity:
100
80
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
93.3
100
100
P-Site Similarity:
100
86.6
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
93.3
100
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
100
0
0
0
0
91
0
% D
% Glu:
0
0
0
0
100
0
0
0
0
100
0
0
0
0
0
% E
% Phe:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% H
% Ile:
0
0
0
0
0
19
100
0
0
0
0
0
100
0
0
% I
% Lys:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
82
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _